THERAPY DOSSIER · th-7c8aa3eaab8c

Danning tablet, a traditional Chinese composite herbal prescription containing anthraquinones, flavonoids and stilbene

Nutraceutical · Nutraceutical (Danning tablet, TCM herbal composite); not a ChEMBL entity

Evidence & regulatory context

Mechanism: Nutraceutical (Danning tablet, TCM herbal composite); not a ChEMBL entity
Target: Not recorded
Injury models: Chemical/toxin
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 1

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT05668871 ↗PHASE4completed

Danning Tablet Under Lifestyle Intervention in Patients With Gallbladder Polyps

Gallbladder Polyps

Enrolment: 326 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 22274634 ↗2012Reported benefit

Protective effect of Danning tablet on acute livery injury with cholestasis induced by alpha-naphthylisothiocyanate in rats.

RatChemical/toxinWistarmaleintragastric3, 1.5 or 0.75 g/kg body weight per dayfor seven days before ANIT administration

Model: alpha-naphthylisothiocyanate (ANIT) 60 mg/kg intragastrically, inducing acute liver injury with cholestasis

Danning tablet 3 g/kg significantly reversed ANIT-induced changes in bile flow, serum liver enzymes and bilirubin and normalised hepatic antioxidant enzyme activities, with partial protection at 1.5 g/kg and no effect at 0.75 g/kg.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.

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