Drug · ChEMBL compound_search returned 0 hits for 'PRT060318' (Portola preclinical selective Syk inhibitor). CTgov has no trials of PRT060318 itself; the 67 keyword hits are fostamatinib, a different approved Syk inhibitor (e.g. NCT00706342, NCT02612558), deliberately NOT used as a match. Flagged for manual review.
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
No linked human trial in this dataset.
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Arterial/vascular injury with thrombosis and neointima formation
Syk inhibition attenuated arterial thrombosis and neointima formation after vascular injury with minimal impact on bleeding.
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.
