Meloxicam 7.5mg vs Diclofenac 100mg SR in Osteoarthritis of the Knee
Osteoarthritis
Enrolment: 91 · Results not recorded
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Drug · Cyclooxygenase (COX) inhibitor (INHIBITOR); parent CHEMBL139
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Osteoarthritis
Enrolment: 91 · Results not recorded
Chronic Low Back Pain
Enrolment: 401 · Results not recorded
Pain
Enrolment: 196 · Results not recorded
Fever
Enrolment: 2 · Results not recorded
Anal Fissure · Rectal Fistula · Hemorrhoids
Enrolment: 120 · Results not recorded
Otitis Externa
Enrolment: 20 · Results not recorded
Patellofemoral Pain Syndrome
Enrolment: 68 · Results not recorded
Drug Interaction
Enrolment: 30 · Results not recorded
Neuralgia · Complex Regional Pain Syndrome
Enrolment: 35 · Results not recorded
Sciatica
Enrolment: 324 · Results not recorded
Neck Pain
Enrolment: 60 · Results not recorded
Subacromial Impingement Syndrome
Enrolment: 70 · Results not recorded
Adhesive Capsulitis of Shoulder
Enrolment: 45 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Caerulein 50 micrograms per kg in 50 microlitres of 0.9 percent NaCl injected intraperitoneally seven times at 1 hour intervals under ketamine and xylazine anaesthesia; animals fasted 12 hours beforehand and killed 6 hours after the last injection
Diclofenac sodium alone significantly reduced lung oedema, congestion and mononuclear inflammation, but kidney improvements were not significant and combination with octreotide significantly increased gastric neutrophil inflammation.
Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.
Model: Acute Achilles tendon injury (tendinopathy)
Tendons treated with phonophoresis plus diclofenac plus gold nanoparticles showed a significant decrease in interleukin-1 beta and tumour necrosis factor alpha, indicating that gold nanoparticles enhanced drug action when used with phonophoresis.
Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.