THERAPY DOSSIER · th-7419c502b508

Mallotus philippinensis fruit glandular hair 50 per cent ethanol extract (MPE)

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Wound
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 25925413 ↗2015Reported benefit

Mallotus philippinensis Muell. Arg fruit glandular hairs extract promotes wound healing on different wound model in rats.

RatWoundCharles FosterMale and femalen = Six rats per group; five groups in the incision model and t…Oral100, 200 and 400 mg/kg in the incision wound dose response;…Commenced after wounding

Model: Incision wound (two 6 cm paravertebral incisions), excision wound (dorsal interscapular circular excision) and dead space wound

Wound breaking strength rose dose dependently (323.3 plus or minus 10.5, 368.3 plus or minus 10.1 and 418.4 plus or minus 14.0 g at 100, 200 and 400 mg/kg versus 291.7 plus or minus 14.2 g in controls). Contraction was faster and epithelialisation period and scar area smaller. Free radical markers…

Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.

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