Evidence & regulatory context
- Mechanism
- Not recorded
- Target
- Not recorded
- Injury models
- TBI
- Reported indication
- Not recorded
- First approval
- Not recorded
- Development stage
- Not recorded
- ChEMBL record
- Not recorded
- ChEMBL max phase
- Not recorded
- Synonyms
- Not recorded
- Note
- Not recorded
Clinical trials 10
1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Effects of The Removal of Myoglobin With CytoSorb on The Endothelium and Glycocalyx Shedding Biomarkers in Patients With Rhabdomyolysis
Acute Kidney Injury · Rhabdomyolysis · Endothelial Dysfunction
Enrolment: 17 · Results not recorded
Data Collection on the Application of Cytokine Adsorption Therapy on Patients With Acute Respiratory Failure Caused by COVID-19
SARS-CoV-2 · COVID-19
Enrolment: 0 · Results not recorded
Cytokine Filter Usage During Open Thoracoabdominal Aortic Aneurysm Repair - Cytosorb and Its Impact on Open TAAA Repair Outcome
Postoperative Complications · Inflammatory Response
Enrolment: 20 · Results not recorded
Retrospective Analysis of the Influence of Cytosorb on Catecholamine Reduction and Mortality in SIRS and Sepsis
Sepsis · Septic Shock · Cytokine Storm · Cytokine Release Syndrome · Catecholamine
Enrolment: 86 · Results not recorded
Hemoadsorption With CytoSorb in Post-Cardiac Arrest Syndrome: a Pilot Study (CATCH Trial)
Cardiac Arrest
Enrolment: 21 · Results not recorded
Effect of CytoSorb Adsorber on Hemodynamic and Immunological Parameters in Critical Ill Patients With COVID-19
COVID-19
Enrolment: 24 · Results not recorded
Effect of the CytoSorb Adsorber on Hemodynamic, Immunological and Pharmacokinetic Parameters in Refractory Septic Shock
Septic Shock
Enrolment: 32 · Results not recorded
Standard Medical Care Plus CytoSorb 300 mL Device Compared to Standard Medical Care Alone in Acute on Chronic Liver Failure Due to Severe Alcoholic Hepatitis
Acute on Chronic Liver Failure · Alcoholic Hepatitis
Enrolment: 0 · Results not recorded
ECMOsorb Trial - Impact of a VA-ECMO in Combination With CytoSorb in Critically Ill Patients With Cardiogenic Shock
Cardiogenic Shock
Enrolment: 42 · Results not recorded
Effects of Renal Replacement Therapy With Hemoadsorption in Patients With Sepsis
Sepsis
Enrolment: 30 · Results not recorded
Preclinical evidence 1
1 studies reported at therapy level; 1 evidence entries itemised.
RatTBIControlled cortical impactSprague DawleyMaleExtracorporeal blood circulation through a treatment cartridgeAfter combined injury, following instrumentation with the extracorporeal circuit
Model: Controlled cortical impact traumatic brain injury combined with pressure-controlled haemorrhagic shock
Survival rose from 47 per cent in sham-treated rats to 86 per cent in haemoadsorption-treated rats, with altered circulating mediator concentrations during and after treatment and no treatment-related histological changes.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
