Celecoxib

Examination of the Effects of Celecoxib on Postmastectomy Seroma and Wound Healing.

Model: Unilateral mastectomy with axillary lymph node dissection (Harada model) via midline incision, skin and subcutaneous flap elevation and excision of pectoralis major, producing postoperative seroma

Mean seroma volume 1.19 +/- 0.074 ml in controls versus 0.333 +/- 0.024 ml with celecoxib (p<=0.001), and seroma fluid IL-1 beta significantly lower with celecoxib (p=0.014). VEGF did not differ (p=0.447) and no histopathological parameter differed except congestion, which was significantly higher…

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Celecoxib reduces the effects of acute and chronic UVB exposure in mice treated with therapeutically relevant immunosuppressive drugs

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Inhibition of ultraviolet light B-induced cutaneous inflammation by a specific cyclooxygenase-2 inhibitor

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Topical application of a selective cyclooxygenase inhibitor suppresses UVB mediated cutaneous inflammation

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The effects of celecoxib, a COX-2 selective inhibitor, on acute inflammation induced in irradiated rats

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Inhibition of cutaneous ultraviolet light B-mediated inflammation and tumor formation with topical celecoxib treatment

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A cyclooxygenase-2 inhibitor impairs ligament healing in the rat

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Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, and indomethacin against ultraviolet light-induced skin carcinogenesis

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