Mepilex Ag versus silver sulfadiazine in deep partial thickness burn injuries
Burn Injuries
Enrolment: 162 · Results not recorded
Loading the evidence…
Drug · Topical antimicrobial foam combining green-synthesised pectin-capped silver nanoparticles with sulfadiazine; a device/drug composite with no ChEMBL entity for the formulation (silver sulfadiazine itself is a long-marketed topical antibacterial). FLAGGED: to_trial=true is CLASS-LEVEL - the trials retained test marketed silver dressings and silver sulfadiazine cream or a silver-nanoparticle irrigant, not the pectin-capped nano-silver foam.
2 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Burn Injuries
Enrolment: 162 · Results not recorded
Second Degree Burn
Enrolment: 100 · Results not recorded
Limb Ischaemia · Diabetes Mellitus
Enrolment: 100 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Superficial second degree (partial thickness) thermal burn wound
The foam had a mean globule size under 75 nm and viscosity around 10 cP, caused no skin irritation, gave higher skin deposition of sulfadiazine, and produced marked wound contraction and evident skin tissue regeneration on histology.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.