THERAPY DOSSIER · th-65cd0f8d6d62

Intravenous fluid resuscitation (water, sodium and albumin loads)

Procedure

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Burn
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 8

3 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT05559489 ↗Injury indicationPHASE3unknown

Implementation of an Enteral Resuscitation Bundle for the Moderate-sized Burn at Kirtipur Hospital, Nepal

Burn Body Region Unspecified · Burn Shock

Enrolment: 240 · Results not recorded

NCT05054270 ↗Injury indicationPhase not recordedcompleted

Efficacy of Lung Ultrasound in Monitoring Fluid Resuscitation in Trauma Patients

Contusions Pulmonary · Lung Injury · Chest Trauma · Fluid Overload Pulmonary Edema

Enrolment: 100 · Results not recorded

NCT06109714 ↗Injury indicationNAnot yet recruiting

Early Biomarker Kidney Injury Assessment After Acumen Directed Fluid Management in Cardiac Surgery

Renal Injury · Acute Kidney Injury

Enrolment: 100 · Results not recorded

NCT01309724 ↗NAcompleted

Hemodynamic Optimization by Non-invasive Determination of Cardiac Output in Critically Ill Patients: a Randomized, Controlled Trial

Hypotension

Enrolment: 92 · Results not recorded

NCT02977429 ↗NAunknown

Clinical Study of Central Venous-to-Arterial Carbon Dioxide Difference (Pcv-aCO2) in the Evaluation of Fluid Therapy for Postoperative Patients With Abdominal Cancer

Abdominal Tumor · Abdominal Infection

Enrolment: 150 · Results not recorded

NCT07670390 ↗Phase not recordednot yet recruiting

Tissue Perfusion Pressure for Predicting Fluid Responsiveness in Patients With Shock: A Prospective Observational Study

Shock

Enrolment: 34 · Results not recorded

NCT04759989 ↗NAterminated

Fluid Resuscitation in Septic Shock Patients With BMI Elevation

Sepsis · Septic Shock · Obesity

Enrolment: 7 · Results not recorded

NCT04180553 ↗NAunknown

Ultrasound-Guided Resuscitation in Open Aortic Surgery

Aortic Diseases

Enrolment: 40 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 7469559 ↗1981Mixed findings

The relationship between experimental fluid therapy and wound edema in scald wounds.

RatBurnScaldMaleIntravenousIntravenous water loads up to 40% of body weight; sodium 0…Acutely after thermal injury

Model: Thermal scald burn wound

Wound oedema increased linearly with the net volume of fluid administered and was largely independent of sodium or albumin content, so composition made no measurable difference while volume increased oedema.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.

Loading the evidence…