THERAPY DOSSIER · th-647d6be98e57

Light-emitting diode phototherapy at 940 nm

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Other
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 5

1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT06113614 ↗Injury indicationNAunknown

Photobiomodulation on functional recovery of proximal humerus fractures

Bone Fracture · Humerus Fracture · Surgery

Enrolment: 42 · Results not recorded

NCT05344222 ↗NAcompleted

Infrared LED photobiomodulation conditioning of orofacial tissue in third molar surgery

Impacted Third Molar Tooth

Enrolment: 62 · Results not recorded

NCT03724552 ↗NAcompleted

Transcranial LED therapy in youth and adults with autism spectrum disorder

Autism · Autism Spectrum Disorder

Enrolment: 12 · Results not recorded

NCT06292819 ↗NAcompleted

Photobiomodulation, bright light and near-infrared light, for insomnia in the elderly

Photobiomodulation · Insomnia

Enrolment: 60 · Results not recorded

NCT04417738 ↗NAcompleted

Unilateral transcranial photobiomodulation, near-infrared mode, for opioid cravings

Opioid-use Disorder · Depression, Anxiety · Craving

Enrolment: 22 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 22223060 ↗2012Reported benefit

Effects of light emitting diode (LED) therapy and cold water immersion therapy on exercise-induced muscle damage in rats.

RatOtherWistarMalen = 32 male Wistar rats allocated to four groups (control, exer…Transcutaneous irradiation of both gastrocnemius muscles940 nm, 4 J/cm2 per gastrocnemius muscleImmediately after the swimming bout and blood sampling

Model: Exercise-induced muscle damage from a single acute 100 minute swimming bout

The LED group showed fewer areas of muscle damage and inflammatory cell infiltration and lower creatine kinase activity than the exercised untreated group, and fewer areas of damaged muscle fibre than cold water immersion. Neither treatment reduced oedema area, and neither affected leukocyte counts.

Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.

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