Human Clinical Trial to Investigate the Effects of High Rosmarinic Acid Spearmint Tea on Markers of Pain, Physical Function and Disease Activity in Osteoarthritis of the Knee
Osteoarthritis of the Knee
Enrolment: 49 · Results not recorded
Nutraceutical
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Osteoarthritis of the Knee
Enrolment: 49 · Results not recorded
Sleep · Mood · Cognitive Performance
Enrolment: 105 · Results not recorded
Pulmonary Tuberculosis · Gastro-Intestinal Disorder
Enrolment: 200 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Acute inflammation by intradermal sub-plantar injection of 100 microlitres of 1% lambda-carrageenan in saline into the left hind paw of rats, and chronic colitis by intracolonic administration of 100 microlitres of 2.5% TNBS in 50% ethanol in mice
Spearmint extract reduced carrageenan-induced paw oedema by 36% (24 +/- 16% versus 60 +/- 20% in the carrageenan group, p < 0.01), with an effect similar to indomethacin, trolox and tempol. In TNBS colitis it produced shorter and less severe lesions, a histological score of about 1 with some areas…
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.