THERAPY DOSSIER · th-58d2db938836

Ethanolic extract of Pterodon pubescens fruits (EEPp)

Nutraceutical · search_trials 'Pterodon pubescens' returned 0 human trials, an explicitly searched zero. Crude botanical extract with no ChEMBL entity.

Non-drug Suggest a correction

Evidence & regulatory context

Mechanism: search_trials 'Pterodon pubescens' returned 0 human trials, an explicitly searched zero. Crude botanical extract with no ChEMBL entity.
Target: Not recorded
Injury models: Other
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 26386380 ↗2015Reported benefit

Ameliorative potential of standardized fruit extract of Pterodon pubescens Benth on neuropathic pain in mice: Evidence for the mechanisms of action.

MouseOtherFemaleIntragastric (oral)30 to 300 mg/kg

Model: Partial sciatic nerve ligation induced neuropathic pain

EEPp reduced mechanical and thermal hyperalgesia after partial sciatic nerve ligation without inducing tolerance, inhibited nociceptive responses to glutamatergic agonists, proinflammatory cytokines and TRPV1 and TRPA1 activators, and showed a cumulative effect over 24 hours on day 15 of prolonged…

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.

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