THERAPY DOSSIER · th-5670ef5fd8e4

Collagen conduit with anti-inflammatory agent (diclofenac)

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Other
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 21783293 ↗2011Reported benefit

Is there a role for a collagen conduit and anti-inflammatory agent in the management of partial peripheral nerve injuries?

RatOtherSprague-DawleyMalen = 10 per groupSurgical implantationAt injury (acute)

Model: Sciatic nerve chronic constriction injury (partial)

A collagen conduit with an anti-inflammatory agent reduced pain and oedema after partial sciatic nerve injury.

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.

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