The Effects of Various Cooking Oils on Health Related Biomarkers in Healthy Subjects
Colorectal Neoplasms
Enrolment: 17 · Results not recorded
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Nutraceutical · Crude plant-derived oil; no single ChEMBL entity. Not resolvable to a defined ChEMBL molecule.
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Colorectal Neoplasms
Enrolment: 17 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Ethanol-induced acute gastric mucosal injury; in vitro work in RGM-1 rat gastric mucosal cells
Ethanol raised the histological injury score to 3.40 plus or minus 0.7 and the haemorrhage score to 2.60 plus or minus 0.5 from 0.00 in controls, and camellia oil at 2 mL/kg significantly reduced both scores while improving antioxidant and heat shock protein responses and lowering inflammatory and…
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.
Model: Ketoprofen 50 mg/kg/day induced acute gastric and intestinal mucosal ulceration
Camellia oil pre-treatment inhibited COX-2 expression, reduced interleukin-6 and nitric oxide production, reversed impairment of the antioxidant system and strongly reduced histologically confirmed gastrointestinal mucosal injury caused by ketoprofen.
Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.