Pilot study of different bindarit dosages in preventing stent restenosis
Coronary Restenosis
Enrolment: 148 · Results not recorded
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Drug
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Coronary Restenosis
Enrolment: 148 · Results not recorded
Diabetic Nephropathy
Enrolment: 100 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Radiation-induced normal lung tissue toxicity after irradiation in mice, with acute vascular dysfunction and late endothelial cell loss and fibrosis; CCR2 knockout mice used as a genetic comparison
Bindarit counteracted radiation-induced Ccl2 expression, normalised endothelial cell morphology and vascular function, and limited lung inflammation and metastasis as acute effects; comparable vascular protection occurred in CCR2 knockout mice, and long-term Ccl2 signalling inhibition limited endot…
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.