Development of hyaluronan-based membranes for the healing of intestinal surgical wounds: a preliminary study.
RatWoundImplantation in direct contact with the intestine
Model: Preliminary in vivo biocompatibility study with implantable membranes placed in direct contact with rat intestine, in the context of intestinal surgical wounds
The membranes dissolved within a few days, were biocompatible in vitro and stimulated wound healing with liquid extracts, and in rats did not elicit acute adverse or immune reactions, with only a mild inflammatory reaction at the mesenteric or serosal region.
Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.