Evaluation of the Effect of Gabexate Mesilate in the Hepatocyte Protection After Liver Resection
Liver Disease
Enrolment: 2 · Results not recorded
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Drug
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Liver Disease
Enrolment: 2 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Traumatic pancreatitis with grade II pancreas injury
Trypsin activity was slightly inhibited at 1.0 and 5.0 mg/mL and completely inhibited at 10.0 and 20.0 mg/mL. Amylase, C-reactive protein and trypsinogen activation peptide were raised in traumatic pancreatitis and were slightly reduced by 1.0 and 5.0 mg/mL gel (p<0.05) and significantly reduced by…
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
Model: Grade III pancreatic trauma, a 0.6 cm laceration with main pancreatic duct rupture created with hemostatic scissors adjacent to the duodenum via midline laparotomy
Gel treatment reduced ascites volume at every time point (2.42 plus or minus 1.24 mL vs 7.92 plus or minus 2.13 mL at 1 h; 4.88 plus or minus 1.29 vs 14.58 plus or minus 1.77 mL at 6 h; 6.17 plus or minus 2.52 vs 18.42 plus or minus 2.75 mL at 24 h, p<0.01). Serum amylase, lipase, C-reactive protei…
Extraction: extract · Supplied extraction confidence: 0.93. Machine-extracted fields require source verification.