Evidence & regulatory context
- Mechanism
- Not recorded
- Target
- Not recorded
- Injury models
- Ischaemia-reperfusion
- Reported indication
- Not recorded
- First approval
- Not recorded
- Development stage
- Not recorded
- ChEMBL record
- Not recorded
- ChEMBL max phase
- Not recorded
- Synonyms
- Not recorded
- Note
- Not recorded
Clinical trials 1
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
An Open Label, Non-randomized, Clinical Study of Chinese Medicine, Sheng-Yu-Tang, for Immune Reconstitution Following Peripheral Blood Stem Cell Transplantation in >CR1 and Refractory Acute Leukemia Patients
Acute Leukemia
Enrolment: 18 · Results not recorded
Preclinical evidence 1
1 studies reported at therapy level; 1 evidence entries itemised.
MouseIschaemia-reperfusionCerebral (MCAO/stroke)Oral1.0 g/kgAfter induction of ischaemic stroke
Model: Acute cerebral ischaemic stroke in mice
Sheng Yu Decoction extended lifespan compared with vehicle, in which over 80 per cent of mice died within 2 days, restored brain function, reduced cerebral infarction and oxidative stress and improved neurological deficits. It significantly altered 162 of 2081 ischaemia-induced probe sets.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.