A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging
Glioblastoma
Enrolment: 18 · Results not recorded
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Nutraceutical
2 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Glioblastoma
Enrolment: 18 · Results not recorded
Glioblastoma Multiforme
Enrolment: 25 · Results not recorded
Neoplasms
Enrolment: 156 · Results not recorded
Healthy · Ketogen-based Therapeutic Diet · Metabolic Abnormalities
Enrolment: 79 · Results not recorded
Delirium · Ketogenic Dieting · Nutrition, Healthy
Enrolment: 90 · Results not recorded
Living-Kidney Donors
Enrolment: 80 · Results not recorded
Critical Illness · Fasting State · Ketosis · Nutrition
Enrolment: 200 · Results not recorded
Nutrition · Muscle Loss · Inflammatory Response
Enrolment: 130 · Results not recorded
Weight Regain Post Bariatric Surgery · Ketogenic Dieting · Intermittent Fasting
Enrolment: 43 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Acute cervical (C5) spinal cord injury; the injury method is not specified in the abstract
All three dietary interventions significantly increased beta-hydroxybutyrate in serum and cerebrospinal fluid and inhibited spinal cord histone deacetylase activity by 31 to 43%. Acetylated histones AcH3K9 and AcH3K14 increased significantly, as did the antioxidant genes Foxo3a and Mt2 and the rela…
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.