Effects of Nutrients Supplementation in Antidepressant Treated Depressive Disorder Patients (erinacine A-enriched Hericium)
Depressive Disorder, Major
Enrolment: 120 · Results not recorded
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Nutraceutical
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Depressive Disorder, Major
Enrolment: 120 · Results not recorded
Healthy Adult Females · Healthy Adult Male
Enrolment: 87 · Results not recorded
Well-Being, Psychological · Mood · Anxiety · Stress
Enrolment: 84 · Results not recorded
Psychological Stress · Anxiety · Depression · Sleep Quality · Cognitive Performance
Enrolment: 67 · Results not recorded
Tinnitus
Enrolment: 80 · Results not recorded
Cognitive Decline
Enrolment: 150 · Results not recorded
Attention
Enrolment: 24 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Global cerebral ischaemia and reperfusion by occlusion of the two common carotid arteries (stroke animal model)
Hericium erinaceus mycelium reduced total infarct volume by 22% at 50 mg/kg and 44% at 300 mg/kg relative to untreated stroke animals, and erinacine A dose dependently reduced infarct volume, inflammatory cytokines, nitrotyrosine, p38 MAPK phosphorylation and CHOP expression.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.