THERAPY DOSSIER · th-33025599e765

Treadmill exercise (low, moderate, high intensity)

Procedure

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Ischaemia-reperfusion
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 6

6 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT01236976 ↗Injury indicationPHASE3completed

SCIPA Full-On: intensive exercise programme (Therastride treadmill) after spinal cord injury

Spinal Cord Injury

Enrolment: 116 · Results not recorded

NCT01349478 ↗Injury indicationPHASE1/PHASE2completed

Robotic-assisted treadmill gait training (LOKOMAT) in complete motor spinal cord injury

Motor Complete Spinal Cord Injury

Enrolment: 11 · Results not recorded

NCT01294332 ↗Injury indicationPHASE1/PHASE2completed

Aerobic exercise training and cardiorespiratory fitness in traumatic brain injury

Traumatic Brain Injury · Physical Fitness · Fatigue

Enrolment: 13 · Results not recorded

NCT06177509 ↗Injury indicationNArecruiting

Graded aerobic exercise in mild traumatic brain injury

Traumatic Brain Injury · Mild Traumatic Brain Injury

Enrolment: 72 · Results not recorded

NCT00619463 ↗Injury indicationNAcompleted

Effects of aerobic exercise on cognition, mood and fatigue following TBI

Traumatic Brain Injury

Enrolment: 154 · Results not recorded

NCT03787199 ↗Injury indicationNAcompleted

Feasibility of overground bodyweight-supporting walking system Andago vs treadmill

Gait Disorders, Neurologic · Cerebral Palsy · Stroke · Traumatic Brain Injury

Enrolment: 20 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 21785345 ↗2011Reported benefit

Effects of exercise of different intensities on the angiogenesis, infarct healing, and function of the left ventricle in postmyocardial infarction rats.

RatIschaemia-reperfusionCardiacSprague-DawleyMale6 weeks of training before acute myocardial infarction

Model: Acute myocardial infarction

Moderate and high intensity exercise before infarction improved LV function, reduced scar size and increased angiogenesis, while low intensity was insufficient.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.

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