Non-Operative Management of TFCC Injuries
Wrist Injuries · PRP
Enrolment: 0 · Results not recorded
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Biologic · Insulin-like growth factor I receptor agonist (AGONIST)
1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Wrist Injuries · PRP
Enrolment: 0 · Results not recorded
Thyroid Eye Disease
Enrolment: 231 · Results not recorded
Crohn Disease
Enrolment: 3 · Results not recorded
Rectal Neoplasms
Enrolment: 11 · Results not recorded
Gulf War Syndrome · Adult Growth Hormone Deficiency
Enrolment: 20 · Results not recorded
Retinopathy of Prematurity
Enrolment: 76 · Results not recorded
Bone Resorption · Osteoporosis
Enrolment: 208 · Results not recorded
Aging
Enrolment: 2120 · Results not recorded
Myotonic Dystrophy
Enrolment: 17 · Results not recorded
Growth Hormone Deficiency
Enrolment: 5 · Results not recorded
Parkinson Disease
Enrolment: 16 · Results not recorded
Progressive Supranuclear Palsy
Enrolment: 6 · Results not recorded
Frailty Syndrome · Heart Failure
Enrolment: 0 · Results not recorded
Mild Cognitive Impairment
Enrolment: 3 · Results not recorded
Idiopathic Short Stature
Enrolment: 275 · Results not recorded
IGF1 Deficiency
Enrolment: 40 · Results not recorded
Growth Hormone Deficiency · Growth Hormone Treatment
Enrolment: 12 · Results not recorded
Type 2 Diabetes · Metabolic Dysfunction-Associated Steatotic Liver Disease
Enrolment: 84 · Results not recorded
Dry Eye Syndrome (DES)
Enrolment: 10 · Results not recorded
Anorexia Nervosa · Osteopenia · Osteoporosis
Enrolment: 148 · Results not recorded
3 studies reported at therapy level; 3 evidence entries itemised.
Model: Controlled cortical impact traumatic brain injury
Continuous intracerebroventricular IGF-1 begun 15 min after controlled cortical impact produced a dose-dependent increase in hippocampal immature neurons, restoring density to sham levels, raised hippocampal Akt activation and improved motor and cognitive function over 7 days, with a therapeutic wi…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.
Model: Autologous blood injection into the striatum (75 microlitres in rats, 20 microlitres in mice); separate heterochronic versus isochronic parabiosis experiment in aged mice before intracerebral haemorrhage
Young plasma significantly reduced mortality and neurological deficit scores in aging rats after intracerebral haemorrhage compared with old plasma or saline, with lower perihaematomal brain water content, less oedema, necrosis and inflammatory infiltration, fewer Fluoro-Jade B positive degeneratin…
Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.
Model: Acute volumetric muscle loss created by surgical excision of 40 per cent of the tibialis anterior muscle, defect approximately 7 mm by 2 mm by 3 mm
In vitro, myotubes on IGF-1 scaffolds were longer (339 plus or minus 66 versus 204 plus or minus 14 micrometres) with more nuclei per myotube (9.5 plus or minus 1.7 versus 5.3 plus or minus 0.4). In vivo, IGF-1 scaffolds with exercise increased perfused vessel density more than 3-fold versus scaffo…
Extraction: extract · Supplied extraction confidence: 0.92. Machine-extracted fields require source verification.