Influence of Oral Telithromycin vs. Azithromycin on Endogenous Microflora in Acute Sinusitis
Maxillary Sinusitis
Enrolment: 192 · Results not recorded
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Drug · Bacterial 70S ribosome inhibitor
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Maxillary Sinusitis
Enrolment: 192 · Results not recorded
Chronic Obstructive Pulmonary Disease
Enrolment: 72 · Results not recorded
Yaws
Enrolment: 16000 · Results not recorded
Respiratory Tract Infection Viral
Enrolment: 0 · Results not recorded
Lyme Disease
Enrolment: 32 · Results not recorded
Crohn Disease · Pediatric Crohns Disease
Enrolment: 13 · Results not recorded
Graves Ophthalmopathy
Enrolment: 0 · Results not recorded
Interstitial Lung Disease
Enrolment: 30 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Transient focal cerebral ischaemia by intraluminal filament occlusion of the middle cerebral artery for 2 h (or 4.5 h in the time-window experiment) followed by reperfusion
A single dose reduced ischaemic brain damage dose-dependently, cut oedema at 22 h of reperfusion (vehicle 85.7 plus or minus 19.9 mm3 versus azithromycin 25.2 plus or minus 9.6 mm3), reduced infarct volume and neurological deficit up to 7 days, remained effective when given after 4.5 h of occlusion…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.95. Machine-extracted fields require source verification.
Model: Lethal total body irradiation followed by allogeneic bone marrow and splenic T cell transplantation, inducing noninfectious lung injury and acute graft-versus-host disease
Preventive azithromycin improved survival and reduced noninfectious lung injury, with improved pulmonary function, reduced inflammatory infiltrates, less collagen deposition and lower lung cytokine and chemokine expression. Intestinal graft-versus-host disease improved at week 6 and liver disease a…
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.