THERAPY DOSSIER · th-2f9049bb7489

Self-assembling peptide nanofiber scaffold (SAPNS)

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Haemorrhage/shock
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 1

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT05581173 ↗Phase not recordedcompleted

Multicenter Prospective Evaluation of the Efficacy of a Self-Assembling Matrix Forming Gel to Prevent Stricture Formation in High-Risk Patients

Esophageal Stricture · Stricture

Enrolment: 41 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 24907463 ↗2014Reported benefit

A self-assembling nanomaterial reduces acute brain injury and enhances functional recovery in a rat model of intracerebral hemorrhage.

RatHaemorrhage/shockUnspecifiedSprague-DawleyMaleLocal intracerebral delivery into the hematoma cavityAfter ultra-early hematoma aspiration

Model: Intracerebral haemorrhage with ultra-early hematoma aspiration

Locally delivered scaffold replaced the hematoma, reduced acute brain injury and cavity formation, and improved sensorimotor functional recovery.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.

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