THERAPY DOSSIER · th-2f482aa17e7e

Acorus calamus extract

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Radiation
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 20605086 ↗2010Reported benefit

Protection from lethal and sub-lethal whole body exposures of mice to gamma-radiation by Acorus calamus L.: studies on tissue antioxidant status and cellular DNA damage.

MouseRadiationMaleOral250 mg/kg1 h prior to irradiation

Model: Whole body gamma-irradiation (lethal 10 Gy and sub-lethal doses)

Acorus calamus extract raised antioxidant defences, reduced DNA damage and modestly improved survival after irradiation.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.

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