Autologous Bone Marrow-derived MSCs Versus Tension-free Vaginal Tape for Female Stress Urinary Incontinence
Urinary Incontinence, Stress
Enrolment: 50 · Results not recorded
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Biologic · Cell therapy; not a defined chemical entity, no ChEMBL record.
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Urinary Incontinence, Stress
Enrolment: 50 · Results not recorded
Chronic Graft-versus-host-disease
Enrolment: 84 · Results not recorded
Parkinson's Disease
Enrolment: 45 · Results not recorded
Ileal Pouch · Crohn Disease
Enrolment: 24 · Results not recorded
Parkinson's Disease
Enrolment: 20 · Results not recorded
COVID-19
Enrolment: 20 · Results not recorded
Diabetes Mellitus, Type 1
Enrolment: 20 · Results not recorded
Aplastic Anemia
Enrolment: 9 · Results not recorded
Liver Cirrhosis
Enrolment: 40 · Results not recorded
Leg Length Inequality
Enrolment: 6 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Combined acid plus small non-acidified particle (CASP) gastric aspiration lung injury given intratracheally
BMSCs reduced alveolar oedema and lung inflammation, raised PaO2, IL-10 and 15d-PGJ2 and lowered wet to dry ratio, BALF protein and cell counts, TNF-alpha, CINC-1 and phospho-p65.
Extraction: extract · Supplied extraction confidence: 0.92. Machine-extracted fields require source verification.
Model: Vaginal distension (serial dilation with 24-32 F bougie dilators then modified 10-F Foley catheter inflated with 3 cc sterile water for 4 h) simulating birth-trauma injury to the continence mechanism
Leak-point pressure after both systemic and periurethral hMSC treatment was comparable with non-distended controls at 4, 10 and 14 days, whereas saline and dermofibroblast controls were significantly lower at days 4 and 14. Connective tissue area proportion was higher in locally treated hMSC animal…
Extraction: extract · Supplied extraction confidence: 0.95. Machine-extracted fields require source verification.