Evidence & regulatory context
- Mechanism
- Not recorded
- Target
- Not recorded
- Injury models
- Burn
- Reported indication
- Not recorded
- First approval
- Not recorded
- Development stage
- Not recorded
- ChEMBL record
- Not recorded
- ChEMBL max phase
- Not recorded
- Synonyms
- Not recorded
- Note
- Not recorded
Clinical trials 1
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Post-marketing safety surveillance of Compound Kuh-seng (Sophora flavescens, matrine-containing) injection: a registry study
Safety Surveillance · Adverse Drug Events · Adverse Drug Reactions · Severe Adverse Events · Severe Adverse Reactions
Enrolment: 30283 · Results not recorded
Preclinical evidence 1
1 studies reported at therapy level; 1 evidence entries itemised.
MouseBurnUnspecifiedMaleAfter burn injury
Model: Acute thermal burn injury
Matrine improved anxiety-like and depression-like behaviour after burn injury, reduced proinflammatory cytokines, malondialdehyde and nitric oxide in hippocampus and prefrontal cortex, restored antioxidant status, corticosterone and BDNF/VEGF, and downregulated JNK/caspase-3.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.