Clinical Trial of Daphnetin Capsules for Lower Limb Lymphoedema Following Gynaecological Surgery
Lower Extremity Lymphedema
Enrolment: 100 · Results not recorded
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Nutraceutical · No curated mechanism of action in ChEMBL. Natural product coumarin (7,8-dihydroxycoumarin), max_phase -1 (unknown clinical phase).
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Lower Extremity Lymphedema
Enrolment: 100 · Results not recorded
Epithelial Ovarian Cancer
Enrolment: 98 · Results not recorded
Cerebrovascular Disorders
Enrolment: 206 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Endotoxin (lipopolysaccharide) induced acute lung injury
Daphnetin conferred substantial protection from endotoxin-induced acute lung injury with reduced inflammatory mediator production, airway response and inflammatory cell infiltration, acting largely through induction of TNFAIP3 and suppression of NF-kappaB; the benefit was partially abrogated by TNF…
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.