THERAPY DOSSIER · th-274fc0d5fede

Low-level laser therapy with an AlGaAs laser (780 nm)

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Crush
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 7

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT06717633 ↗PHASE3unknown

Short-term Effects of ESWT, Low-level Laser Therapy and Pulsed Electromagnetic Field Therapy in Knee Osteoarthritis

Knee Osteoarthritis

Enrolment: 120 · Results not recorded

NCT01972100 ↗NAcompleted

Low-level Laser Therapy (808nm) to Muscle Fatigue Resistance: Randomized Double-blind Crossover Trial

Healthy

Enrolment: 7 · Results not recorded

NCT07303192 ↗NAcompleted

Injectable Platelet-Rich Fibrin and Low-Level Laser Therapy on Graft Shrinkage in Free Gingival Grafts

Graft Shrinkage · Gingival Recession, Localized

Enrolment: 48 · Results not recorded

NCT06520761 ↗NAunknown

Injectable Platelet Rich Fibrin Versus Low-Level LASER Therapy on Rate of Orthodontic Tooth Movement

Rate of Canine Retraction · Root Resorption

Enrolment: 20 · Results not recorded

NCT05689593 ↗NAcompleted

Low Intensity Extracorporeal Shock Wave Therapy vs Low Intensity Laser Therapy in Adhesive Capsulitis

Adhesive Capsulitis

Enrolment: 65 · Results not recorded

NCT07613489 ↗NAactive not recruiting

Photobiomodulation Therapy in Enhancing Nerve Function and Quality of Life in Diabetic Peripheral Neuropathy

Diabetic Peripheral Neuropathy · Diabetes Mellitus Type 2

Enrolment: 36 · Results not recorded

NCT05279911 ↗NAcompleted

Low-level Laser Therapy on Radiographic and Biochemical Profiles in Type II Diabetic Patients After Dental Implant Insertion

Type 2 Diabetes Mellitus · Low-level Laser Therapy

Enrolment: 40 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 23982721 ↗2013Reported benefit

Modulating effect of low level-laser therapy on fibrosis in the repair process of the tibialis anterior muscle in rats.

RatCrushLimb / muscle crushWistarMalen = Control n=10, sham n=10, laser n=30, non-treated injury n=3…Transcutaneous irradiation of the injured muscleBeam spot 0.04 cm2, output power 40 mW, power density 1 W/c…Daily after cryoinjury

Model: Cryoinjury of the belly of the tibialis anterior muscle

Laser therapy reduced inflammatory infiltrate and myonecrosis at 1 day, increased blood vessel numbers at 3 and 7 days and increased immature muscle fibres and MMP-2 gelatinase activity at 7 days, with improved collagen organisation.

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.78. Machine-extracted fields require source verification.

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