Argatroban IV vs Desirudin SC for Suspected Heparin-Induced Thrombocytopenia
Suspected Heparin-Induced Thrombocytopenia
Enrolment: 16 · Results not recorded
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Drug · Thrombin inhibitor (INHIBITOR)
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Suspected Heparin-Induced Thrombocytopenia
Enrolment: 16 · Results not recorded
CVD
Enrolment: 114 · Results not recorded
CVD
Enrolment: 114 · Results not recorded
Argatroban, Rt-PA
Enrolment: 3 · Results not recorded
Gynecologic Neoplasms · Venous Thromboembolism
Enrolment: 315 · Results not recorded
ECMO Complication
Enrolment: 40 · Results not recorded
Ischemic Stroke
Enrolment: 30 · Results not recorded
Heparin-induced Thrombocytopenia
Enrolment: 200 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Middle cerebral artery occlusion focal cerebral ischemia
Intra-arterial thrombin during ischemia significantly increased vascular disruption and cellular injury and caused cognitive deficit, whereas intravenous argatroban alleviated neurovascular injury and preserved learning and memory. Thrombin proteolytic activity was specifically associated with neur…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.
Model: Acute subdural haemorrhage produced by subdural infusion of 300 microlitres of autologous venous blood at 50 microlitres per minute
Neither local thrombin inhibition nor PAR1 blockade significantly reduced 14-day lesion volume or neurological deficit, showing only non-significant trends towards benefit.
Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.