Ampakine CX717 vs Placebo in Adults With ADHD
Attention Deficit Hyperactivity Disorder
Enrolment: 68 · Results not recorded
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Drug · Ampakine; AMPA receptor positive allosteric modulator (no ChEMBL mechanism record).
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Attention Deficit Hyperactivity Disorder
Enrolment: 68 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Left C2 lateral spinal cord hemisection (C2Hx) via C2 laminectomy, studied at 2 or 8 weeks post-injury under urethane anaesthesia with bilateral phrenic nerve recording
Intravenous CX717 produced a rapid and sustained bilateral increase in phrenic inspiratory burst amplitude at both 2 and 8 weeks post-injury, and restored quantifiable ipsilateral bursting in rats with absent baseline output. Pairing with a single hypoxic bout was inconsistent, with variable enhanc…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.95. Machine-extracted fields require source verification.