Evidence & regulatory context
- Mechanism
- Not recorded
- Target
- Not recorded
- Injury models
- Other
- Reported indication
- Not recorded
- First approval
- Not recorded
- Development stage
- Not recorded
- ChEMBL record
- Not recorded
- ChEMBL max phase
- Not recorded
- Synonyms
- Not recorded
- Note
- Not recorded
Clinical trials 1
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Hypotaurine Supplementation in Freezing and Preparation Media Improves Human Sperm DeoxyriboNucleic Acid (DNA) and Fertilizing Ability
Cryopreservation · Human Spermatozoa Parameters · Hypotaurine Supplementation · Spermatozoa DNA Alterations
Enrolment: 33 · Results not recorded
Preclinical evidence 1
1 studies reported at therapy level; 1 evidence entries itemised.
RatOtherSprague-DawleyMaleIntrathecal100, 200, 400 and 600 micrograms intrathecally; antagonist…
Model: Chronic constriction injury of the sciatic nerve for neuropathic pain, plus formalin-induced inflammatory nociception and tail flick and paw pressure tests for acute thermal and mechanical nociception
Intrathecal hypotaurine produced antinociception against thermal, mechanical and chemical nociception, and alleviated mechanical allodynia and thermal hyperalgesia in chronic constriction injury rats. These effects were completely reversed by intrathecal strychnine, and motor performance on the Rot…
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.