Safety and efficacy of umbilical cord blood mononuclear cells in radiation-induced lung injury
Radiation-induced Lung Injury
Enrolment: 10 · Results not recorded
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Biologic
2 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Radiation-induced Lung Injury
Enrolment: 10 · Results not recorded
Spinal Cord Contusion
Enrolment: 20 · Results not recorded
Bronchopulmonary Dysplasia
Enrolment: 140 · Results not recorded
Cerebral Palsy
Enrolment: 150 · Results not recorded
Autism Spectrum Disorder
Enrolment: 30 · Results not recorded
Knee Osteoarthritis
Enrolment: 30 · Results not recorded
Ischemic Bowel Disease
Enrolment: 100 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Acute lethal total body irradiation with 9 to 10 Gy of caesium-137 gamma rays delivered at 1 Gy/min in a ventilated irradiator
More than 93 per cent of mice given 2 x 10^8 cord blood mononucleated cells plus Levaquin survived to 50 days, significantly better than irradiation alone (P less than 0.01). The 1 x 10^8 dose with Levaquin gave 66 per cent survival (P = 0.08), Levaquin alone 58 per cent and cord blood alone 36 per…
Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.