Head Cooling in Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy: A Phase 2 Randomised Controlled Trial (COOLHEAD-2b)
Acute Ischemic Stroke · Reperfusion Injury
Enrolment: 182 · Results not recorded
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Device
1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Acute Ischemic Stroke · Reperfusion Injury
Enrolment: 182 · Results not recorded
Hypothermia · Stroke, Acute
Enrolment: 120 · Results not recorded
Mental Health · Neurological Health
Enrolment: 24 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Transient and permanent middle cerebral artery occlusion
The device produced rapid and accurate cerebral hypothermia without altering core temperature and reduced acute ischaemic neuronal death, reperfusion injury, progressive penumbral damage and oedema formation.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.