Long-term safety of retigabine IR in adults with partial-onset seizures
Epilepsy
Enrolment: 98 · Results not recorded
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Drug · KCNQ (Kv7) potassium channel opener
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Epilepsy
Enrolment: 98 · Results not recorded
Seizures
Enrolment: 306 · Results not recorded
Epilepsy · Epilepsy in Children · Brain Diseases
Enrolment: 8 · Results not recorded
Epilepsy · Epilepsy in Children
Enrolment: 8 · Results not recorded
Epilepsy
Enrolment: 5 · Results not recorded
Major Depressive Disorder · Depression
Enrolment: 18 · Results not recorded
Epilepsy
Enrolment: 30 · Results not recorded
Epilepsy
Enrolment: 1 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Contusive spinal cord injury at T10
Osmotic pump delivery started 3 hours after contusion improved locomotor recovery, whereas intraperitoneal delivery did not. Both delivery methods attenuated mechanical hyperreflexia and spontaneous pain, with no change in thermal threshold. Treatment started 3 days after injury reduced mechanical…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
Model: Controlled closed-cortical impact blunt traumatic brain injury
Systemic retigabine given 30 min after injury reduced the post-injury cascade including spontaneous seizures, chemo-convulsant susceptibility, metabolic stress, inflammation, blood-brain barrier breakdown and cell death.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.