THERAPY DOSSIER · th-113f4be8a63c

human fat graft

Procedure

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Radiation
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 5

1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT05610878 ↗Injury indicationPHASE1recruiting

Supplementation of autologous fat grafts with curcumin-preconditioned adipose-derived stem cells in facial contour deformities

Romberg Disease · Craniofacial Microsomia · Burn Scar · Post-Traumatic Scar

Enrolment: 24 · Results not recorded

NCT00616135 ↗PHASE4completed

Adipose-derived regenerative cells (ADRC-enhanced autologous fat transplant) in breast deformities post segmental resection

Breast Neoplasms · Breast Reconstruction

Enrolment: 71 · Results not recorded

NCT02809001 ↗PHASE1/PHASE2completed

The effects of autologous fat transfer on preventing expanded skin from expansion failure

Scar · Nevus

Enrolment: 80 · Results not recorded

NCT02339779 ↗NAactive not recruiting

Breast reconstruction with external pre-expansion and autologous fat transfer versus standard therapy

Breast Cancer

Enrolment: 196 · Results not recorded

NCT05482425 ↗NAcompleted

Skin characteristics after facial autologous fat grafting using saline-washed or unwashed fat graft

Facial Skin Texture · Facial Skin Pigmentation

Enrolment: 26 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 21502909 ↗2011Reported benefit

Human fat grafting alleviates radiation skin damage in a murine model.

MouseRadiationFVB (wild-type)subcutaneous graft1.5 cc4 weeks after irradiation

Model: localised skin irradiation (45 Gy) radiodermatitis

Human fat grafting improved gross skin appearance, reduced epidermal thickness and scar index in irradiated murine skin.

Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.

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