THERAPY DOSSIER · th-0d370b745457

Eccentric training, with or without platelet-rich plasma injection

Procedure

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Other
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 28291948 ↗2017Mixed findings

Eccentric Training for Tendon Healing After Acute Lesion: A Rat Model.

RatOtherSprague-Dawleymaleeccentric exercise training; intralesional injection of physiological fluid or homologous platelet-rich plasmainjection at the time of lesion; training commenced after surgery

Model: Surgical incision in the middle of the left patellar tendon

Eccentric training increased ultimate tensile force at rupture by 4.5 N (108 per cent of control, P = 0.006) regardless of injectate, while platelet-rich plasma alone gave no significant benefit over physiological fluid.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.

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