Nicotinamide Riboside and Pterostilbene Supplementation on Muscle Regeneration in Elderly Humans
Muscle Injury
Enrolment: 32 · Results not recorded
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Nutraceutical
1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Muscle Injury
Enrolment: 32 · Results not recorded
Atypical Endometrial Hyperplasia · Endometrial Carcinoma
Enrolment: 44 · Results not recorded
AKI
Enrolment: 54 · Results not recorded
Amyotrophic Lateral Sclerosis
Enrolment: 90 · Results not recorded
Recovery of Function
Enrolment: 48 · Results not recorded
Healthy
Enrolment: 0 · Results not recorded
Safety: Healthy Subjects
Enrolment: 120 · Results not recorded
Biological Availability
Enrolment: 6 · Results not recorded
Menopause
Enrolment: 40 · Results not recorded
Amyotrophic Lateral Sclerosis
Enrolment: 380 · Results not recorded
3 studies reported at therapy level; 3 evidence entries itemised.
Model: Neonatal hypoxic-ischaemic brain damage in postnatal day 7 rat pups
Pterostilbene pretreatment reduced infarct volume, brain oedema and neurological score and improved motor coordination and working memory, with lower proinflammatory cytokines, less programmed cell death and reduced oxidative stress, all reversed by the heme oxygenase-1 inhibitor zinc protoporphyri…
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.
Model: Acute renal ischaemia-reperfusion by left renal pedicle clamping for 20 minutes followed by reperfusion
Ischaemia-reperfusion increased membrane fluidity and reduced the lipid to protein ratio. The magnetic field alone restored some but not all changes and increased inner membrane disorder. The combination of pterostilbene and magnetic field restored the lipid to protein ratio, hydrocarbon chain leng…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.
Model: UVB radiation-induced skin damage and photocarcinogenesis; acute UVB at 360 mJ/cm2 and chronic UVB at 180 mJ/cm2 three doses per week for 6 months; parallel in vitro work in HaCaT immortalised human keratinocytes
Pterostilbene prevented acute UVB-induced increases in skin fold, thickness and redness and photoaging-associated wrinkling and hyperplasia, and prevented chronic UVB-induced skin carcinogenesis, with 90% of pterostilbene-treated mice free of skin carcinomas versus numerous tumours in all controls.…
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.