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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

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PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2017

PMID 28448872Rat

Curcumin attenuates lipopolysaccharide/d-galactosamine-induced acute liver injury by activating Nrf2 nuclear translocation and inhibiting NF-kB activation.

Endotoxin/LPS1 linked therapy

2017

PMID 28452872Rat

Combination therapy of levetiracetam and gabapentin against nonconvulsive seizures induced by penetrating traumatic brain injury.

TBI1 linked therapy

2017

PMID 28453954Rat

Local delivery of chondroitinase ABC with or without stromal cell-derived factor 1alpha promotes functional repair in the injured rat spinal cord.

Spinal cord injury1 linked therapy

2017

PMID 28456012Rat

Neuregulin-1 positively modulates glial response and improves neurological recovery following traumatic spinal cord injury.

Spinal cord injury1 linked therapy

2017

PMID 28456613Mixed

E-Cadherin-Mediated Cell Contact Controls the Epidermal Damage Response in Radiation Dermatitis.

Radiation1 linked therapy

2017

PMID 28460454Rat

Inhibition of epidermal growth factor receptor attenuates LPS-induced inflammation and acute lung injury in rats.

Endotoxin/LPS1 linked therapy

2017

PMID 28464953Mouse

The efficacy of human placenta-derived mesenchymal stem cells on radiation enteropathy along with proteomic biomarkers predicting a favorable response.

Radiation1 linked therapy

2017

PMID 28466227Rat

Protective Effects and Mechanisms of Shenhua Tablet on Toll-Like Receptors in Rat Model of Renal Ischemia-Reperfusion Injury.

Ischaemia-reperfusion1 linked therapy

2017

PMID 28471234Rat

Protective effects of diltiazem and tadalafil on shock wave-induced kidney injury in rats.

Ischaemia-reperfusion1 linked therapy

2017

PMID 28472639Rat

Post-injury administration of a combination of memantine and 17beta-estradiol is protective in a rat model of traumatic brain injury.

TBI1 linked therapy

2017

PMID 28474970Rat

Ellagic acid protects against arsenic trioxide-induced cardiotoxicity in rat.

Chemical/toxin1 linked therapy

2017

PMID 28478272Rat

The pivotal role of HIF-1alpha in lung inflammatory injury induced by septic mesenteric lymph.

Other1 linked therapy

2017

PMID 28482882Mouse

Targeted siRNA delivery reduces nitric oxide mediated cell death after spinal cord injury.

Spinal cord injury1 linked therapy

2017

PMID 28487990Rat

Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats.

Haemorrhage/shock1 linked therapy

2017

PMID 28488390Mouse

Mesenchymal stem cells protect from acute liver injury by attenuating hepatotoxicity of liver natural killer T cells in an inducible nitric oxide synthase- and indoleamine 2,3-dioxygenase-dependent manner.

Chemical/toxin1 linked therapy

2017

PMID 28490163Rat

Effects of Quercetin and Mannitol on Erythropoietin Levels in Rats Following Acute Severe Traumatic Brain Injury.

TBI1 linked therapy

2017

PMID 28493078Mouse

The 5-HTReceptor Antagonist Ondansetron Attenuates Pancreatic Injury in Cerulein-Induced Acute Pancreatitis Model.

Chemical/toxin1 linked therapy

2017

PMID 28493083Rat

Protective Effects of Acupuncture in Cardiopulmonary Bypass-Induced Lung Injury in Rats.

Other1 linked therapy

2017

PMID 28493985Mouse

Photodynamic antimicrobial chemotherapy with the novel amino acid-porphyrin conjugate 4I: In vitro and in vivo studies.

Wound1 linked therapy

2017

PMID 28494415Rat

Studies on curative efficacy of monoterpene eugenol on anti-leukemic drug arsenic trioxide induced cardiotoxicity.

Chemical/toxin1 linked therapy

2017

PMID 28498296Mouse

Interleukin-22 Prevents Microbial Dysbiosis and Promotes Intestinal Barrier Regeneration Following Acute Injury.

Burn1 linked therapy

2017

PMID 28502961Rat

Haptoglobin Reduces Inflammatory Cytokine INF-gamma and Facilitates Clot Formation in Acute Severe Burn Rat Model.

Burn1 linked therapy

2017

PMID 28508172Rat

Targeting Enolase in Reducing Secondary Damage in Acute Spinal Cord Injury in Rats.

Spinal cord injury1 linked therapy

2017

PMID 28510617Mouse

miR-146a-5p acts as a negative regulator of TGF-beta signaling in skeletal muscle after acute contusion.

Crush1 linked therapy

2017

PMID 28520687Rat

3% NaCl adenosine, lidocaine, Mg2+ (ALM) bolus and 4 hours drip infusion reduces noncompressible hemorrhage by 60% in a rat model.

Haemorrhage/shock1 linked therapy

2017

PMID 28526985Rat

Salidroside Attenuates LPS-Induced Acute Lung Injury in Rats.

Endotoxin/LPS1 linked therapy

2017

PMID 28527718Rat

Rotenone decreases ischemia-induced injury by inhibiting mitochondrial permeability transition in mature brains.

Ischaemia-reperfusion1 linked therapy

2017

PMID 28529754Mouse

Chitosan-Poly(caprolactone) Nanofibers for Skin Repair.

Wound1 linked therapy

2017

PMID 28530769Rat

Beneficial effects of garlic (Allium sativum) oil in experimental corrosive esophageal burns effects of garlic oil in esophageal burns.

Burn1 linked therapy

2017

PMID 28530785Rat

Anti-edematous, anti-inflammatory and neuroprotective effect of etanercept in acute stage in experimental head injury.

TBI1 linked therapy

2017

PMID 28531920Mixed

Wound healing and anti-inflammatory activity of some Ononis taxons.

Wound1 linked therapy

2017

PMID 28533328Rat

Tendon stem/progenitor cells regulate inflammation in tendon healingJNK and STAT3 signaling.

Other1 linked therapy

2017

PMID 28538627Mouse

Early heparin administration after traumatic brain injury: Prolonged cognitive recovery associated with reduced cerebral edema and neutrophil sequestration.

TBI1 linked therapy

2017

PMID 28539419Mouse

Microglia Are Irrelevant for Neuronal Degeneration and Axon Regeneration after Acute Injury.

Crush1 linked therapy

2017

PMID 28542295Rat

Therapeutic benefits of phosphodiesterase 4B inhibition after traumatic brain injury.

TBI1 linked therapy

2017

PMID 28542361Mouse

Granulocyte colony-stimulating factor blockade enables dexamethasone to inhibit lipopolysaccharide-induced murine lung neutrophils.

Endotoxin/LPS1 linked therapy

2017

PMID 28544974Mixed

Cetuximab modified collagen scaffold directs neurogenesis of injury-activated endogenous neural stem cells for acute spinal cord injury repair.

Spinal cord injury1 linked therapy

2017

PMID 28548957Mixed

Involvement of p38-betaTrCP-Tristetraprolin-TNFalpha axis in radiation pneumonitis.

Radiation1 linked therapy

2017

PMID 28549897Rat

Daily acute intermittent hypoxia improves breathing function with acute and chronic spinal injury via distinct mechanisms.

Spinal cord injury1 linked therapy

2017

PMID 28552531Rat

A causal relationship between the neurotherapeutic effects of miR182/7a and decreased expression of PRDM5.

Spinal cord injury1 linked therapy

2017

PMID 28552717Rat

Exploring acute-to-chronic neuropathic pain in rats after contusion spinal cord injury.

Spinal cord injury1 linked therapy

2017

PMID 28561222Rat

Cromolyn Sodium Attenuates Paraquat-Induced Lung Injury by Modulation of Proinflammatory Cytokines.

Chemical/toxin1 linked therapy

2017

PMID 28562049Mouse

Protective Effect of Camellia Oil (Camellia oleifera Abel.) against Ethanol-Induced Acute Oxidative Injury of the Gastric Mucosa in Mice.

Chemical/toxin1 linked therapy

2017

PMID 28562485Mouse

Antihyperalgesic effect by herpes vector-mediated knockdown of NaV1.7 sodium channels after skin incision.

Wound1 linked therapy

2017

PMID 28566468Mouse

Smad7 protects against acute kidney injury by rescuing tubular epithelial cells from the G1 cell cycle arrest.

Ischaemia-reperfusion1 linked therapy

2017

PMID 28566747Mouse

Novel Locally Active Estrogens Accelerate Cutaneous Wound Healing-Part 2.

Wound1 linked therapy

2017

PMID 28570981Mouse

Ethyl pyruvate alleviates radiation-induced lung injury in mice.

Radiation1 linked therapy

2017

PMID 28572712Rat

Methylprednisolone Administration Following Spinal Cord Injury Reduces Aquaporin 4 Expression and Exacerbates Edema.

Spinal cord injury1 linked therapy

2017

PMID 28577538Rat

Dai-Huang-Fu-Zi-Tang alleviates pulmonary and intestinal injury with severe acute pancreatitis via regulating aquaporins in rats.

Chemical/toxin1 linked therapy

2017

PMID 28594313Mouse

Protection against TBI-Induced Neuronal Death with Post-Treatment with a Selective Calpain-2 Inhibitor in Mice.

TBI1 linked therapy

1,401–1,450 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.