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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

A project by Pebble.

PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2020

PMID 30829389Rat

Evaluation of the Efficacy of Sildenafil Citrate Following Severe Head Trauma in an Experimental Rat Model.

TBI1 linked therapy

2020

PMID 30892165Mouse

Mitigation of Radiation-induced Pneumonitis and Lung Fibrosis using Alpha-lipoic Acid and Resveratrol.

Radiation1 linked therapy

2020

PMID 31228183Mixed

Levosimendan prevents doxorubicin-induced cardiotoxicity in time- and dose-dependent manner: implications for inotropy.

Chemical/toxin1 linked therapy

2020

PMID 31259781Rat

Activation of Hypoxia-Inducible Factor-1alpha Via Succinate Dehydrogenase Pathway During Acute Lung Injury Induced by Trauma/Hemorrhagic Shock.

Haemorrhage/shock1 linked therapy

2020

PMID 31400763Rat

Histopathological Changes of Organs (Lungs, Liver, Kidney, and Brain) After Using Two Types of AgiCoat and Acticoat Nanosilver Dressings on Deep Second-Degree Burn in Rat.

Burn1 linked therapy

2020

PMID 31407065Mouse

The Role of Galectin-3 in Subarachnoid Hemorrhage: A Preliminary Study.

Haemorrhage/shock1 linked therapy

2020

PMID 31488552Rat

Hypoxia-Inducible Factor 1alpha (HIF-1alpha) Counteracts the Acute Death of Cells Transplanted into the Injured Spinal Cord.

Spinal cord injury1 linked therapy

2020

PMID 31626023Rat

Human neural stem cell transplant location-dependent neuroprotection and motor deficit amelioration in rats with penetrating traumatic brain injury.

TBI1 linked therapy

2020

PMID 31634234Mixed

Agmatine Protects Against the Progression of Sepsis Through the Imidazoline I2 Receptor-Ribosomal S6 Kinase 2-Nuclear Factor-kappaB Signaling Pathway.

Endotoxin/LPS1 linked therapy

2020

PMID 31638090Rat

Inhibiting endogenous tissue plasminogen activator enhanced neuronal apoptosis and axonal injury after traumatic brain injury.

TBI1 linked therapy

2020

PMID 31688783Mixed

Is all plasma created equal? A pilot study of the effect of interdonor variability.

Haemorrhage/shock1 linked therapy

2020

PMID 31774030Rat

Extracellular Vesicles Mediate Neuroprotection and Functional Recovery after Traumatic Brain Injury.

TBI1 linked therapy

2020

PMID 31791444Mouse

Metformin ameliorates bile duct ligation-induced acute hepatic injury via regulation of ER stress.

Other1 linked therapy

2020

PMID 31830804Mouse

Malabaricone C Attenuates Nonsteroidal Anti-Inflammatory Drug-Induced Gastric Ulceration by Decreasing Oxidative/Nitrative Stress and Inflammation and Promoting Angiogenic Autohealing.

Chemical/toxin1 linked therapy

2020

PMID 31881612Rat

Creating a Favorable Microenvironment for Fat Grafting in a Novel Model of Radiation-Induced Mammary Fat Pad Fibrosis.

Radiation1 linked therapy

2020

PMID 31896131Rat

Effects of a potassium channel opener on brain injury and neurologic outcomes in an animal model of neonatal hypoxic-ischemic injury.

Ischaemia-reperfusion1 linked therapy

2020

PMID 31903774Mouse

Neural stem cell-derived exosomes facilitate spinal cord functional recovery after injury by promoting angiogenesis.

Spinal cord injury1 linked therapy

2020

PMID 31914449Mouse

Effects of Receptor for Advanced Glycation End-Products (RAGE) Signaling on Intestinal Ischemic Damage in Mice.

Ischaemia-reperfusion1 linked therapy

2020

PMID 31918005Rat

Protective effect of curcumin nanoparticles against cardiotoxicity induced by doxorubicin in rat.

Chemical/toxin1 linked therapy

2020

PMID 31918060Mouse

Ghrelin alleviates traumatic brain injury-induced acute lung injury through pyroptosis/NF-kB pathway.

TBI1 linked therapy

2020

PMID 31921518Mouse

A transcriptomic study of probenecid on injured spinal cords in mice.

Spinal cord injury1 linked therapy

2020

PMID 31924689Rat

Carbon Monoxide Rescues the Developmental Lethality of Experimental Rat Models of Rhabdomyolysis-Induced Acute Kidney Injury

Crush1 linked therapy

2020

PMID 31925846Mouse

Intravenous Immunomodulatory Nanoparticle Treatment for Traumatic Brain Injury

TBI1 linked therapy

2020

PMID 31928642Mouse

Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System

Radiation1 linked therapy

2020

PMID 31928923Rat

Immunohistochemical and histological evaluations of cyclophosphamide-induced acute cardiotoxicity in wistar rats: The role of turmeric extract (curcuma)

Chemical/toxin1 linked therapy

2020

PMID 31929529Mouse

Chemical profiling of Curatella americana Linn leaves by UPLC-HRMS and its wound healing activity in mice

Wound1 linked therapy

2020

PMID 31933513Rat

Abdominal paracentesis drainage ameliorates myocardial injury in severe experimental pancreatitis rats through suppressing oxidative stress

Chemical/toxin1 linked therapy

2020

PMID 31934739Mouse

Biguanide-Derived Polymeric Nanoparticles Kill MRSA Biofilm and Suppress Infection.

Wound1 linked therapy

2020

PMID 31935495Rat

Vincetoxicum arnottianum ameliorate inflammation by suppressing oxidative stress and pro-inflammatory mediators in rat.

Chemical/toxin1 linked therapy

2020

PMID 31941605Mouse

Gracillin inhibits apoptosis and inflammation induced by lipopolysaccharide (LPS) to alleviate cardiac injury in mice via improving miR-29a.

Endotoxin/LPS1 linked therapy

2020

PMID 31941655Mouse

Glycyrrhizin Protects gamma-Irradiated Mice from Gut Bacteria-Associated Infectious Complications by Improving RNA Reduction in Macrophages of the Bacterial Translocation Site.

Radiation1 linked therapy

2020

PMID 31953218Mouse

Arachidonic acid inhibits inflammatory responses by binding to myeloid differentiation factor-2 (MD2) and preventing MD2/toll-like receptor 4 signaling activation.

Endotoxin/LPS1 linked therapy

2020

PMID 31960049Rat

Neuroprotection in the Acute Stage Enables Functional Recovery Following Repair of Chronic Cervical Root Transection After a 3-Week Delay.

Other1 linked therapy

2020

PMID 31961020Rat

HMGB1-associated necroptosis and Kupffer cells M1 polarization underlies remote liver injury induced by intestinal ischemia/reperfusion in rats.

Ischaemia-reperfusion1 linked therapy

2020

PMID 31961718Mouse

Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome.

Radiation1 linked therapy

2020

PMID 31964241Rat

Sesamin promotes angiogenesis and accelerates wound healing in rats via alleviates TBHP-induced apoptosis in human umbilical vein endothelial cells.

Wound1 linked therapy

2020

PMID 31965620Mouse

Photobiomodulation does not influence maturation and mildly improves functional healing of mouse achilles tendons.

Other1 linked therapy

2020

PMID 31969383Rat

Enhancing KCNQ Channel Activity Improves Neurobehavioral Recovery after Spinal Cord Injury.

Spinal cord injury1 linked therapy

2020

PMID 31970778Mouse

Anti-inflammatory effect of octyl gallate in alveolar macrophages cells and mice with acute lung injury.

Endotoxin/LPS1 linked therapy

2020

PMID 31971040Mouse

Immunomodulatory role of recombinant human erythropoietin in acute kidney injury induced by crush syndrome inhibition of the TLR4/NF-kappaB signaling pathway in macrophages.

Crush1 linked therapy

2020

PMID 31972209Rat

The molecular mechanism underlining the preventive effect of vitamin D against hepatic and renal acute toxicity through the NrF2/ BACH1/ HO-1 pathway.

Chemical/toxin1 linked therapy

2020

PMID 31973660Rat

Acute Cardiovascular Responses to Vagus Nerve Stimulation after Experimental Spinal Cord Injury.

Spinal cord injury1 linked therapy

2020

PMID 31982303Mouse

Topical transient receptor potential ankyrin 1 antagonist treatment attenuates nociception and inflammation in an ultraviolet B radiation-induced burn model in mice.

Burn1 linked therapy

2020

PMID 31985636Mouse

Noncontact Phased-Array Ultrasound Facilitates Acute Wound Healing in Mice.

Wound1 linked therapy

2020

PMID 31989134Rat

Implantation of a functional TEMPO-hydrogel induces recovery from rat spinal cord transection through promoting nerve regeneration and protecting bladder tissue.

Spinal cord injury1 linked therapy

2020

PMID 31989756Mouse

Chicoric acid ameliorate inflammation and oxidative stress in Lipopolysaccharide and d-galactosamine induced acute liver injury.

Endotoxin/LPS1 linked therapy

2020

PMID 31991111Mouse

Cardiac Nestin+ Mesenchymal Stromal Cells Enhance Healing of Ischemic Heart through Periostin-Mediated M2 Macrophage Polarization.

Ischaemia-reperfusion1 linked therapy

2020

PMID 31991372Mouse

Protective effect of diallyl disulfide against cerulein-induced acute pancreatitis and associated lung injury in mice.

Chemical/toxin1 linked therapy

2020

PMID 31996011Rat

Effects of electroacupuncture on functional indices and pS6 expression following acute sciatic nerve crush injury in rats.

Crush1 linked therapy

2020

PMID 31999976Rat

Scutellarin protects against myocardial ischemia-reperfusion injury by suppressing NLRP3 inflammasome activation.

Ischaemia-reperfusion1 linked therapy

1–50 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.