The effect of acute haemorrhage and of delayed blood replacement on wound healing: an experimental study.
RatHaemorrhage/shockControlledWistarn = Controls n = 7, haemorrhage n = 6, replacement n = 6 at 6 w…Replacement of 10 ml/kg shed blood1 hour after haemorrhage
Model: Median laparotomy wound with acute haemorrhage of 10 ml/kg, either untreated or with delayed replacement
At 6 weeks bursting pressure was significantly lower in both the haemorrhage group (181.7, SEM 30.5 mmHg; P = 0.026) and the replacement group (207.8, SEM 27.4 mmHg; P = 0.037) than in controls (301.9, SEM 42.0 mmHg), with less abundant and less organised collagen in both bled groups. By 3 months n…
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.