Immunodepression, a noncontributor to radiation-induced leukemogenesis of the RFM mouse.
MouseRadiationRFMFemale50 x 10^6 cellsImmediately following X-irradiation
Model: Single acute whole-body exposure to 300 R of X-rays
Spleen cells restored immunocompetence more rapidly but did not protect against radiation-induced thymic lymphoma, whereas bone marrow cells did not accelerate immune recovery yet markedly reduced mortality.
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