Macroscopic and histologic tissue reaction to polydioxanone, a new, synthetic, monofilament microsuture.
RatOtherFemalen = Three to four animals killed at each of 3, 7, 14, 30 and 60…Surgical implantation6-0 or 8-0 gaugeAt the time of anastomosis
Model: Microsurgical anastomosis of the bicornuate uterus, right horn versus left horn within the same animal
Polydioxanone was histologically more inert than Vicryl and provoked a less intense acute and chronic inflammatory response. Macroscopically, adhesion formation was quantitatively reduced around polydioxanone-treated horns and most such adhesions were avascular.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.