Efficacy of polyglycolic acid (Dexon) microsutures in peripheral nerve anastomoses in the rat: 2. Perineural suture.
RatOtherLewisMalen = 48 rats with Dexon repair plus 8 additional rats with nylon…Surgical implantation10-0 gaugeAt the time of nerve repair
Model: Bilateral sciatic nerve transection with perineural repair
Dexon-sutured nerve segments showed an acute inflammatory cellular reaction that gradually subsided, with foreign body giant cells persisting around sutures for up to 68 days and absent thereafter. With nylon, foreign body giant cells and a lymphocytic infiltrate persisted around the suture for 6 m…
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