The effects of calcium dobesilate on acute lymphedema (with and without macrophages), and on burn edema.
RatBurnUnspecifiedMale
Model: Burn oedema of the rat foot and acute lymphoedema of the rat thigh, with and without macrophage depletion by silica
A low dose reduced burn oedema of the rat foot whereas a high dose had no effect. Acute lymphoedema of the rat thigh was greatly reduced, to 26 per cent, although oedema in the foot was not. Electron microscopy showed increased tissue macrophage numbers and reduced protein concentrations. Destroyin…
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