Delayed treatment with nerve growth factor reverses the apparent loss of cholinergic neurons after acute brain damage.
RatTBIUnspecifiedIntraventricularDelayed treatment started 1, 2 and 3 weeks after injury, once most neurons were…
Model: Axotomy of septal cholinergic neurons by acute brain damage (fimbria-fornix type lesion)
NGF started 1, 2 or 3 weeks after axotomy caused a marked reappearance of apparently lost septal cholinergic neurons, indicating the loss reflects reduced detectability of neurotransmitter enzyme rather than neuronal death.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.