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PRECLINICAL PUBLICATION · 2020

Okra pectin relieves inflammatory response and protects damaged intestinal barrier in caerulein-induced acute pancreatic model.

Mouse / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 33433910 ↗2020Reported benefit

Okra pectin relieves inflammatory response and protects damaged intestinal barrier in caerulein-induced acute pancreatic model.

MouseChemical/toxinMaleDietary supplementationGiven in advance of induction of pancreatitis

Model: Caerulein-induced acute pancreatitis with associated intestinal barrier damage

Dietary okra pectin reduced serum amylase and lipase, pancreatic oedema, myeloperoxidase activity and pro-inflammatory cytokines while preserving tight junction and antimicrobial peptide expression, with purified pectin outperforming the crude preparation.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.