Evaluation of Anti-Inflammatory and Antiapoptotic Effects of Bone Marrow and Adipose-Derived Mesenchymal Stem Cells in Acute Alkaline Corneal Burn.
RatBurnChemical / corrosiveSprague-Dawleymalen = 32 rats in 4 groups, 8 per group (n = 8)subconjunctival injection2 x 10 (exponent not recoverable from the retrieved text) m…After creation of the alkaline burn; exact interval not stated
Model: Acute alkaline corneal burn produced under general anaesthesia by applying 4 microlitres of NaOH on 6 mm filter paper to the right eye
IL-1 beta and TNF-alpha staining scores and numbers of CD68 and caspase-3 positive cells were significantly lower in both mesenchymal stem cell groups than in the alkaline burn control group (P < 0.0001 for all parameters). Epithelial IL-1 beta and TNF-alpha staining scores were significantly lower…
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