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PRECLINICAL PUBLICATION · 2020

COX-2 inhibition does not alter wound healing outcomes of a volumetric muscle loss injury treated with a biologic scaffold.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 33049117 ↗2020No effect reported

COX-2 inhibition does not alter wound healing outcomes of a volumetric muscle loss injury treated with a biologic scaffold.

RatOtherSprague-DawleyMaleAcute administration at the time of injury and scaffold implantation

Model: Surgically created volumetric muscle loss defect treated with an implanted biologic scaffold

Adjunct COX-2 inhibition with mavacoxib did not alter the baseline functional or histomorphological repair outcomes achieved by the biologic scaffold in volumetric muscle loss.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.