A multifunctional shape-adaptive and biodegradable hydrogel with hemorrhage control and broad-spectrum antimicrobial activity for wound healing.
MixedHaemorrhage/shockUncontrolledTopical, injected into or applied to the woundApplied at the time of injury
Model: Rat liver haemorrhage injury model and rat full-thickness skin wound model infected with methicillin-resistant Staphylococcus aureus; biodegradation assessed in mice
The OD/EPL hydrogel promoted blood clotting in vitro and stopped bleeding in a rat liver injury model within 6 minutes through platelet aggregation and a sealing effect. It killed a broad spectrum of pathogens without antibiotics, was biodegradable and cytocompatible, and inhibited MRSA infection w…
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.