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PRECLINICAL PUBLICATION · 2020

Fucoxanthin Mitigates Subarachnoid Hemorrhage-Induced Oxidative Damage via Sirtuin 1-Dependent Pathway.

Mixed / Haemorrhage/shock

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 32876840 ↗2020Reported benefit

Fucoxanthin Mitigates Subarachnoid Hemorrhage-Induced Oxidative Damage via Sirtuin 1-Dependent Pathway.

MixedHaemorrhage/shockUnspecified

Model: Experimental subarachnoid haemorrhage, with parallel experiments in primary cultured neurons

Fucoxanthin inhibited reactive oxygen species production and lipid peroxidation after subarachnoid haemorrhage, restored endogenous antioxidant enzyme activities, improved mitochondrial morphology, reduced neuronal apoptosis and brain oedema, and improved short-term and long-term neurobehavioural f…

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.